- Flying V-shaped mahogany body with bevels, set Dave Mustaine spec D-shaped mahogany neck, 24-fret bound ebony fingerboard with pearl shark's tooth inlays, bound headstock with signature, six-on-one-side tuners, tune-o-matic bridge, V-shaped metal tailpiece, STB, two Dave Mustaine Live Wire covered pickups, three knobs (two v, tone), three-way pickup switch, black hardware, available in Classic Black or Metallic Silver finish, 25.5 in. scale, hardshell case included, mfg. 2007-present.

- similar to the Dave Mustaine Signature, except has a custom "Angel of Deth" graphic finish, mfg. 2008-present.

- similar to the Dave Mustaine Signature, except has a custom "Fear" graphic finish, mfg. 2011-present.

- similar to the Dave Mustaine Signature, except has a double locking Floyd Rose tremolo bridge, available in Classic Black finish, mfg. 2012-present.

- similar to the Dave Mustaine Signature, except has a custom "Gears of War" graphic finish, mfg. summer 2007-2010.

- similar to the Dave Mustaine Signature, except has a custom "Rust in Peace" graphic finish, mfg. 2009-present.

- Flying V-shaped basswood body with bevels, bolt-on Dave Mustaine profile D-shaped maple neck, 24-fret rosewood fingerboard with pearl dot inlays, matching finish headstock with signature, six-on-one-side mini Grover tuners, tune-o-matic bridge, V-shaped metal tailpiece, STB, two Dean Design black exposed humbucker pickups, three knobs, three-way pickup switch, black hardware, available in Classic Black or Metallic Silver finish, 25.5 in. scale, mfg. 2008-present.

- similar to the Dave Mustaine V X, except has a custom "United Abominations" graphic finish, mfg. 2009-present.

- doubleneck configuration with a 12-string neck on the bass side and six-string neck on the treble side, double Flying V-shaped mahogany body with bevels, two set Dave Mustaine spec D-shaped mahogany necks, 24-fret bound ebony fingerboards with pearl shark's tooth inlays (reverse on the 12-string neck), black headstock overlays with Dean logos, six-on-one-side tuners, six tuners on the bottom of the 12-string neck, tune-o-matic bridge, V-shaped metal tailpiece, STB, three Dave Mustaine Duncan Live Wire covered pickups (one on the 12-string neck, two on the six-string neck), three knobs (two v, tone), three-way pickup switch, three-way neck toggle switch, black hardware, available in Classic Black finish, 25.5 in. scale, hardshell case included, mfg. 2011-present.

- Flying V-shaped mahogany body with bevels, set Dave Mustaine profile D-shaped maple neck, 24-fret rosewood fingerboard with pearl dot inlays, matching finish headstock overlay with signature, six-on-one-side mini Grover tuners, tune-o-matic bridge, STB, two DMT Design active pickups, three knobs, three-way pickup switch, black hardware, available in custom "End Game" graphics finish, 25.5 in. scale, mfg. 2010-present.

- Flying V-shaped mahogany body with bevels, set Dave Mustaine profile D-shaped maple neck, 24-fret rosewood fingerboard with pearl dot inlays, black headstock overlay with signature, six-on-one-side mini Grover tuners, tune-o-matic bridge, STB, two DMT Design active pickups, three knobs, three-way pickup switch, black hardware, available in custom "Peace Sells" graphics finish, 25.5 in. scale, mfg. 2012-present.

- Flying V-shaped mahogany body with bevels, flame maple top, D-shaped mahogany neck, 24-fret bound ebony fingerboard with pearl shark's tooth inlays, bound headstock with signature, six-on-one-side tuners, TonePros bridge, V-shaped metal tailpiece, two Seymour Duncan Dave Mustaine Live Wire covered pickups, three knobs, three-way switch, gold hardware, available in Trans. Amber, Trans. Blackburst, or Trans. Red finish, 25.5 in. scale, custom stenciled hardshell case included, mfg. 2007-08.

- double neck configuration with a 12-string neck and six-string neck, double Flying V-style mahogany body with bevels, D-shaped Mustaine profile mahogany necks, 24-fret ebony fingerboards with pearl sharks tooth and small dot inlays, bound headstocks with six-on-on-side tuners (12-string neck has six additional tuners at the bottom of the guitar), Tone Pros tune-o-matic bridges, V-shaped black metal tailpieces, Dave Mustaine Duncan Live Wire pickups (one for the 12-string and two for the six-string), three knobs, three-way pickup switch, neck selector switch, black hardware, available in Blood Lust finish, 25.5 in. scale, Flight Case and Deth Certificate of Authenticity included, limited edition run of 50 instruments, mfg. 2008-present.

- offset hourglass Explorer-style mahogany body with bevels, set Dave Mustaine spec D-shaped mahogany neck, 24-fret bound ebony fingerboard with pearl shark's tooth inlays, bound headstock with signature, six-on-one-side tuners, tune-o-matic bridge, V-shaped metal tailpiece, STB, two Dave Mustaine Duncan Live Wire covered pickups, three knobs (two v, tone), three-way pickup switch, black hardware, available in Classic Black (2013-present), Metallic Silver finish, 25.5 in. scale, hardshell case included, mfg. 2010-present.

- offset hourglass Explorer-style mahogany body with bevels, set Dave Mustaine profile D-shaped maple neck, 24-fret rosewood fingerboard with pearl dot inlays, black headstock overlay with signature, six-on-one-side mini Grover tuners, tune-o-matic bridge, V-shaped tailpiece, STB, two DMT Design active pickups, three knobs, three-way pickup switch, black hardware, available in custom "Angel of Deth II" graphics finish, 25.5 in. scale, mfg. 2011-present.